Reverse triiodothyronine
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Reverse triiodothyronine
| Reverse triiodothyronine | |
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(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl]propanoic acid |
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| Identifiers | |
| CAS number | 5817-39-0  |
| PubChem | 22069 |
| MeSH | Reverse+triiodothyronine |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C15H12I3NO4 |
| Molar mass | 650.974 |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Reverse triiodothyronine (3,3',5'-Triiodothyronine, reverse T3, or rT3) is a molecule that is an isomer of triiodothyronine (T3). It is derived from thyroxine.
rT3 increases in conditions such as sick euthyroid syndrome. rT3 is an inactive form of thyroid hormone.[1] It increases in euthyroid syndrome because its clearance decreases while its production stays the same. The decreased clearance is possibly from lower 5'-deiodinase activity in the peripheral tissue or decreased liver uptake of rT3. [2]
Reactions
References
- ^ Molina PE. Chapter 4. Thyroid Gland. In: Molina PE, ed. Endocrine Physiology. 3rd ed. New York: McGraw-Hill; 2010. http://www.accessmedicine.com/content.aspx?aID=6169456. Accessed May 6, 2012.
- ^ http://emedicine.medscape.com/article/118651-overview#showall
External links
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