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More about Riboflavin Deficiency: Definition Causes and symptoms Diagnosis Treatment Prognosis Prevention Resources

A deficiency only in riboflavin has never occurred in the natural environment. In contrast, diseases where people are deficient in one vitamin, such as thiamin, vitamin C, and vitamin D, for example, have been clearly documented. Poorer populations in the United States may be deficient in riboflavin, but when this happens, they are also deficient in a number of other nutrients as well. When riboflavin deficiency is actually detected, it is often associated with low consumption of milk, chronic alcoholism, or chronic diarrhea.

The symptoms of riboflavin deficiency include:

• swelling and fissuring of the lips (cheilosis)
• ulceration and cracking of the angles of the mouth (angular stomatitisis)
• oily, scaly skin rashes on the scrotum, vulva, or area between the nose and lips
• inflammation of the tongue
• red, itchy eyes that are sensitive to light.

The nervous symptoms of riboflavin deficiency include:

• numbness of the hands
• decreased sensitivity to touch, temperature, and vibration

— Tom Brody, PhD