| Meaning | Category |
| SCSI Configured AutoMatically | Computing->General Computing->Networking Computing->Software |
| Scale Combat Aircraft Modelers | Miscellaneous->Hobbies |
| Sharp Color Active Matrix | Computing->Hardware |
| Simple Compiler to Assembly for Mips | Computing->Software |
| Simple Configure for Automatic Makefiles | Computing->Software |
| Skin, Cass, Ace, Mark (Skunk Anansie rock group) | Community->Music |
| Smart Card Analyzer and Manipulator | Computing->General |
| Sports Cyber Arts Music | Community->Media |
| Stanford Copy Analysis Mechanism | Academic & Science->Universities |
| Still Can't Access Mine! | Miscellaneous->Funnies |
| Substituted Cysteine Accessibility Method | Medical->Human Genome |
| Substituted-cysteine accessibility method | Medical->Laboratory |
| Suffolk College Alternative Music | Academic & Science->Universities |
| The Social Creative Association of Marketing | Miscellaneous->Funnies |
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