SEI may stand for:
- Safety Equipment Institute, a private, non-profit organization established to test safety and protective products
- Seebeck effect imaging, uses a laser to generate thermal gradients in conductors in order to locate electrically floating conductors
- Service endpoint interface, a term used in Java Platform, Enterprise Edition when exposing Enterprise JavaBean as web service
- Software Engineering Institute, a federally funded research and development center at Carnegie Mellon University
- Space Exploration Initiative, a plan envisioned by former U.S. President George H.W. Bush with manned Moon and Mars missions
- Stockholm Environment Institute, a non-profit institute that specializes in sustainable development and environmental issues
For other uses, see Sei (disambiguation).
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