Serine dehydratase

serine dehydratase
Identifiers
Symbol	SDS
Entrez	10993
HUGO	10691
OMIM	182128
RefSeq	NM_006843
UniProt	P20132
Other data
EC number	4.3.1.17
Locus	Chr. 12 q24.21

Serine dehydratase is an enzyme which converts serine to pyruvate. It also converts Threonine to Propionyl CoA.

External links

• MeSH Serine+dehydratase

This biochemistry article is a stub. You can help Wikipedia by expanding it.

v • d • e Carbon-nitrogen lyases (EC 4.3) 4.3.1: ammonia-lyases Histidine ammonia-lyase - Formiminotransferase cyclodeaminase - Serine dehydratase 4.3.2: amidine-lyases Argininosuccinate lyase - Adenylosuccinate lyase

v • d • e Metabolism: amino acid metabolism · synthesis and catabolism enzymes (essential in CAPS) K→acetyl-CoA LYSINE→ Saccharopine dehydrogenase · Glutaryl-CoA dehydrogenase LEUCINE→ Branched chain aminotransferase · Branched-chain alpha-keto acid dehydrogenase complex · Isovaleryl coenzyme A dehydrogenase · Methylcrotonyl-CoA carboxylase · Methylglutaconyl-CoA hydratase · 3-hydroxy-3-methylglutaryl-CoA lyase TRYPTOPHAN→ Indoleamine 2,3-dioxygenase/Tryptophan 2,3-dioxygenase · Arylformamidase · Kynureninase · 3-hydroxyanthranilate oxidase · Aminocarboxymuconate-semialdehyde decarboxylase · Aminomuconate-semialdehyde dehydrogenase PHENYLALANINE→tyrosine→ (see below) G G→pyruvate →citrate glycine→serine→ Serine hydroxymethyltransferase · Serine dehydratase glycine→creatine: Guanidinoacetate N-methyltransferase · Creatine kinase alanine→ Alanine transaminase cysteine→ D-cysteine desulfhydrase threonine→ L-threonine dehydrogenase G→glutamate→ α-ketoglutarate HISTIDINE→ Histidine ammonia-lyase · Urocanate hydratase · Formiminotransferase cyclodeaminase proline→ Proline oxidase · Pyrroline-5-carboxylate reductase · 1-Pyrroline-5-carboxylate dehydrogenase/ALDH4A1 · PYCR1 arginine→ Ornithine aminotransferase · Ornithine decarboxylase · Agmatinase →alpha-ketoglutarate→TCA Glutamate dehydrogenase Other cysteine+glutamate→glutathione: Gamma-glutamylcysteine synthetase · Glutathione synthetase · Gamma-glutamyl transpeptidase glutamate→glutamine: Glutamine synthetase · Glutaminase G→propionyl-CoA→ succinyl-CoA VALINE→ Branched chain aminotransferase · Branched-chain alpha-keto acid dehydrogenase complex · Enoyl-CoA hydratase · 3-hydroxyisobutyryl-CoA hydrolase · 3-hydroxyisobutyrate dehydrogenase · Methylmalonate semialdehyde dehydrogenase ISOLEUCINE→ Branched chain aminotransferase · Branched-chain alpha-keto acid dehydrogenase complex · 3-hydroxy-2-methylbutyryl-CoA dehydrogenase METHIONINE→ generation of homocysteine: Methionine adenosyltransferase · Adenosylhomocysteinase regeneration of methionine: MTR/Homocysteine methyltransferase · Betaine-homocysteine methyltransferase conversion to cysteine: Cystathionine beta synthase · Cystathionine gamma-lyase THREONINE→ Threonine aldolase →succinyl-CoA→TCA Propionyl-CoA carboxylase · Methylmalonyl CoA epimerase · Methylmalonyl-CoA mutase G→fumarate PHENYLALANINE→tyrosine→ Phenylalanine hydroxylase · Tyrosine aminotransferase · 4-Hydroxyphenylpyruvate dioxygenase · Homogentisate 1,2-dioxygenase · Fumarylacetoacetate hydrolase tyrosine→melanin: Tyrosinase G→oxaloacetate asparagine→aspartate→ Asparaginase/Asparagine synthetase · Aspartate transaminase see also disorders, intermediates

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