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Skin lesions can be caused by a wide variety of conditions and diseases. A tendency toward developing moles, freckles, or birthmarks may be inherited. Infection of the skin itself by bacteria, viruses, fungi, or parasites is the most common cause of skin lesions. Acne, athlete's foot (tinea pedis), warts, and scabies are examples of skin infections that cause lesions. Allergic reactions and sensitivity to outside environmental factors can also lead to the formation of skin lesions. Underlying conditions can also precipitate the appearance of skin lesions. For example, the decreased sensitivity and poor circulation that accompanies diabetes mellitus can contribute to the formation of extensive ulcers on extremities such as the feet. Infections of body's entire system can cause the sudden onset of skin lesions. For example, skin lesions are a hallmark symptom of such diseases as chicken pox, herpes, and small pox. Cancers affecting the skin, including basal cell carcinoma, squamous cell carcinoma, malignant melanoma, and Kaposi's sarcoma, are recognized by their lesions.
— Bridget Travers
