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Smoking-Cessation Drugs: Interactions

 
Medical Encyclopedia: Smoking-Cessation Drugs: Interactions
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People taking certain drugs may need to change their doses when they stop smoking. Anyone who uses a smoking cessation drug should let the physician know all other medicines he or she is taking and should ask whether the doses need to be changed. Examples of drugs that may be affected when a person stops smoking are:

  • insulin
  • airway opening drugs (bronchodilators) such as aminophylline (Somophyllin), oxtriphylline (Choledyl) or theophylline (Somophyllin-T)
  • opioid (narcotic) pain relievers such as propoxyphene (Darvon)
  • the beta blocker propranolol (Inderal)

Other drugs may also interact with smoking cessation drugs. Be sure to check with a physician or pharmacist before combining smoking cessation drugs with any other prescription or nonprescription (over-the-counter) medicine.

Bupropion should not be used by patients who are also taking monoamine oxidase inhibitor (MAOI) medications. These include such drugs as furazolidone, isocarboxazid, and phenelzine. Bupropion may also interact with phenytoin, carbamazepine, and levodopa. Buspirone also interacts with MAOIs, as well as with trazadone and haloperidol.

— Rebecca J. Frey, PhD



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