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Spumavirus

 

A member of the subfamily Spumavirinae.

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Spumavirus
Virus classification
Group: Group VI (ssRNA-RT)
Family: Retroviridae
Subfamily: Spumaretrovirinae
Genus: Spumavirus
Type species
Simian foamy virus
Species

African green monkey simian foamy virus
Macaque simian foamy virus
Bovine foamy virus
Equine foamy virus
Feline foamy virus

A spumavirus or foamyvirus is a genus of the retroviridae family. Spumaviruses are exogenous viruses that have specific morphology with prominent surface spikes. The virions contain significant amounts of double-stranded full-length DNA, and assembly is rather unusual in these viruses. Normally, the envelope membrane is acquired by budding through the endoplasmic reticulum. However, in, for example, the equine foamy virus (EFV), budding from the cytoplasmic membrane occurs.

Some examples of this virus are the chimpanzee foamy virus, simian foamy virus and the human foamy virus.

While spumaviruses will form characteristic large vacuoles in their host cells while in vitro, there is no disease association in vivo.[1]

References

  1. ^ Acheson, NH (2007). Fundamentals of Molecular Virology (1st ed. ed.). John Wiley & Sons. ISBN 0-471-35151-2. 

Further reading

  • Santillana-Hayat M, Valla J et al. "Inhibition of the in vitro infectivity and cytopathic effect of human foamy virus by dideoxynucleosides". AIDS Res Hum Retroviruses. 1996 Oct 10; 12(15):1485-90.

External links


 
 
Learn More
syncytium
Retrovirus
Human foamy virus

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Copyrights:

Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Spumavirus" Read more