SSRI

n.
A class of drugs, such as fluoxetine or sertraline, that inhibit the uptake of serotonin by neurons of the central nervous system and are primarily used in the treatment of depression and obsessive compulsive disorder.

[s(elective) s(erotonin) r(euptake) i(nhibitor).]

n.

A class of drugs, as fluoxetine hydrochloride, that inhibit the uptake of serontonin by the central nervous system, often used in the treatment of depression.

Selective serotonin reuptake inhibitor.

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The noun has one meaning:

Meaning #1: an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain
  Synonym: selective-serotonin reuptake inhibitor

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