Yes. Depression is a qualifying condition under Social Security Disability rules, but you would need to have medical documentation and an employment history demonstrating the depression significantly interferes with your ability to engage in substantial gainful activity (SGA). In 2010, SGA is $1,000 per month for most disabilities, and $1,640 for anyone legally blind.
You can learn more about SSDI, SSI and the application process through the Social Security Administration via Related Links and Sources, below.