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tropomodulin 2 (neuronal)
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| Identifiers | |
| Symbol | TMOD2 |
| Entrez | 29767 |
| HUGO | 11872 |
| OMIM | 602928 |
| RefSeq | NM_014548 |
| UniProt | Q9NZR1 |
| Other data | |
| Locus | Chr. 15 q21.2 |
Tropomodulin 2 (neuronal) also known as TMOD2 is a protein which in humans is encoded by the TMOD2 gene.[1]
Function
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.[2]
References
- ^ Cox PR, Zoghbi HY (January 2000). "Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs". Genomics 63 (1): 97–107. doi:. PMID 10662549.
- ^ "Entrez Gene: TMOD2 , Tropomodulin 2 (neuronal)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29767.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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