TMOD3

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Tropomodulin 3 (ubiquitous)
Identifiers
Symbols	TMOD3; UTMOD
External IDs	OMIM: 605112 MGI: 1355315 HomoloGene: 8727
Gene ontology Molecular function • actin binding • tropomyosin binding Cellular component • cytoskeleton • F-actin capping protein complex
Orthologs
Species	Human	Mouse
Entrez	29766	50875
Ensembl	ENSG00000138594	ENSMUSG00000058587
UniProt	Q9NYL9	Q3TFA9
RefSeq	NM_014547 (mRNA)	NM_016963 (mRNA)
	NP_055362 (protein)	NP_058659 (protein)
Location	Chr 15: 49.91 - 49.99 Mb	Chr 9: 75.28 - 75.35 Mb
PubMed search	[1]	[2]

Tropomodulin-3 is a protein that in humans is encoded by the TMOD3 gene.^[1][2]

References

1. ^ Cox PR, Zoghbi HY (Apr 2000). "Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs". Genomics 63 (1): 97-107. doi:10.1006/geno.1999.6061. PMID 10662549. 
2. ^ "Entrez Gene: TMOD3 tropomodulin 3 (ubiquitous)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29766. 

Further reading

• Weber KL, Fischer RS, Fowler VM (2008). "Tmod3 regulates polarized epithelial cell morphology.". J. Cell. Sci. 120 (Pt 20): 3625–32. doi:10.1242/jcs.011445. PMID 17928307. 
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
• Fischer RS, Yarmola EG, Weber KL, et al. (2007). "Tropomodulin 3 binds to actin monomers.". J. Biol. Chem. 281 (47): 36454–65. doi:10.1074/jbc.M606315200. PMID 17012745. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
• Pawlak G, McGarvey TW, Nguyen TB, et al. (2004). "Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder.". Int. J. Cancer 110 (3): 368–73. doi:10.1002/ijc.20151. PMID 15095301. 
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. 
• Fischer RS, Fritz-Six KL, Fowler VM (2003). "Pointed-end capping by tropomodulin3 negatively regulates endothelial cell motility.". J. Cell Biol. 161 (2): 371–80. doi:10.1083/jcb.200209057. PMID 12707310. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 

This article on a gene on chromosome 15 is a stub. You can help Wikipedia by expanding it. v • d • e

v • d • e Proteins of the cytoskeleton Human Microfilaments (ABPs) Myofilament Actins (A1, A2, B, G1, G2) Myosins (1A, 1B, 1C, MYH1, MYH2, MYH3, MYH4, MYH6, MYH7, MYH7B, MYH8, MYH9, MYH10, MYH11, MYH13, MYH14, MYH15, MYH16) Tropomodulin (1, 2, 3, 4) · Troponin (T 1 2 3, C 1 2, I 1 2 3) · Tropomyosin (1, 2, 3, 4) other related: Actinin (1, 2, 3, 4) · Arp2/3 complex · actin depolymerizing factors (Cofilin (1, 2) · Destrin) · Gelsolin · Profilin (1, 2) Other Wiskott-Aldrich syndrome protein IFs type 1 and 2 (Cytokeratin, type I, type II) · type 3 (Desmin, GFAP, Peripherin, Vimentin) · type 4 (Internexin, Nestin, Neurofilament, Synemin, Syncoilin) · type 5 (Lamin A, B) Microtubules Dyneins · Kinesins · MAPs (Tau protein, Dynamin) · Tubulins · Stathmin · Tektin Catenins Alpha catenin · Beta catenin · Plakoglobin (gamma catenin) · Delta catenin Other APC · Dystrophin (Dystroglycan) · plakin (Desmoplakin, Plectin) · Spectrin (SPTA1, SPTAN1, SPTB, SPTBN1, SPTBN2, SPTBN4, SPTBN5) · Talin (TLN1)  · Utrophin · Vinculin Nonhuman Major sperm proteins · Prokaryotic cytoskeleton (Crescentin, FtsZ, MreB)

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