Tolazamide

A first generation sulfonylurea derivative, used as a hypoglycemic agent in the treatment of diabetes mellitus.

The noun has one meaning:

Meaning #1: a drug (trade name Tolinase) used in treating stable adult-onset diabetes mellitus
  Synonym: Tolinase

Tolazamide
Systematic (IUPAC) name
N-[(azepan-1-ylamino)carbonyl]-4-methylbenzenesulfonamide
Identifiers
CAS number	1156-19-0
ATC code	A10BB05
PubChem	5503
DrugBank	APRD01267
Chemical data
Formula	C14H21N3O3S
Mol. mass	311.401 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	7 hours
Excretion	Renal (85%) and fecal (7%)
Therapeutic considerations
Licence data	US FDA:link
Pregnancy cat.	C(AU) C(US)
Legal status	℞-only(US)
Routes	Oral
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Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes. It is part of the sulfonamide family (ATC A10BB).

External links

• NIH/Medline

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