| Toxic multinodular goitre | |
|---|---|
| Classification and external resources | |
| ICD-10 | E05.2 |
| ICD-9 | 242.3 |
| DiseasesDB | 13184 |
| MedlinePlus | 000317 |
| eMedicine | med/920 |
Toxic multinodular goitre (also known as toxic nodular goitre, toxic nodular struma) is a form of hyperthyroidism - where there is excess production of thyroid hormones. It is characterized by functionally autonomous nodules. It emerges insidiously from nontoxic multinodular goitre.
It is the second most common cause of hyperthyroidism after Graves disease.
Contents |
Symptoms
Symptoms of toxic multinodular goitre are similar to that of hyperthyroidism, including:
- heat intolerance
- muscle weakness/wasting
- hyperkinesis
- tremor
- irritability
- weight loss
- osteoporosis
- increased appetite
- goitre (swelling of the thyroid gland)
- tachycardia (high heart rate - above 100 bpm at rest in adults)
Related eponym
Plummer's disease is named after the American physician Henry Stanley Plummer but refers to a single toxic nodule (adenoma) which may present with the background of a suppressed multinodular goitre.[1]
Footnotes
- ^ Plummer's disease eponymously named after Henry Stanley Plummer at Who Named It?
External links
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