toxoid

For more information on toxoid, visit Britannica.com.

Toxins that have been treated to destroy their toxic properties but retain their ability to induce antibody production, thus creating an active immunity.

Toxin that has had its poisonous element removed, but which retains its ability to act as an antigen and stimulate the production of antibodies against the actual toxin.

A toxin treated by heat or chemical agent to destroy its deleterious properties without destroying its antigenicity. Most of the clostridial diseases, e.g. tetanus, are controlled by vaccination with toxoids.

A toxoid is a bacterial toxin (usually an exotoxin) whose toxicity has been weakened or suppressed either by chemical (formalin) or heat treatment, while other properties, typically immunogenicity, are maintained. Toxoids are used in vaccines as they induce an immune response to the original toxin or increase the response to another antigen. For example, the tetanus toxoid is derived from the tetanospasmin produced by Clostridium tetani and causing tetanus. The tetanus toxoid is used by many plasma centers in the United States for the development of plasma rich vaccines.

v • d • e Artificial induction of immunity / Immunization: Vaccines, Vaccination, and Inoculation (J07) Development Adjuvants · Mathematical modelling · Timeline · Trials Classes: Inactivated vaccine · Live vector vaccine (Attenuated vaccine, Heterologous vaccine) · Toxoid · Subunit/component/Virus-like particle · Conjugate vaccine · DNA vaccination Administration Global: GAVI Alliance · Policy · Schedule · Vaccine injury USA: ACIP · VAERS · VSD · Vaccine court Vaccines Bacterial Anthrax · Brucellosis · Cholera# · Diphtheria# · Hib# · Meningococcus# (NmVac4-A/C/Y/W-135, NmVac4-A/C/Y/W-135 - DT, MeNZB) · Pertussis# · Plague · Pneumococcal# (PPSV, PCV) · Tetanus# · Tuberculosis (BCG)# · Typhoid# (Ty21a, ViCPS) · Typhus combination: DTwP/DTaP Viral Adenovirus · Tick-borne encephalitis · Japanese encephalitis# · Flu# (Pandemrix, LAIV, H1N1) · HAV# · HBV# · HPV (Gardasil, Cervarix) · Measles# · Mumps# (Mumpsvax) · Polio# (Salk, Sabin) · Rabies# · Rotavirus# · Rubella# · Smallpox (Dryvax) · Varicella (chicken pox)# · Yellow fever# combination: MMR · MMRV research: Cytomegalovirus · Epstein-Barr · HIV · Hepatitis C Protozoan Malaria · Trypanosomiasis Helminthiasis Schistosomiasis · Hookworm Other TA-CD · NicVAX · Cancer vaccines (ALVAC-CEA vaccine) Controversy General · MMR · NCVIA · Pox party · Simpsonwood · Thiomersal See also List of vaccine topics · Epidemiology · Eradication of infectious diseases #WHO-EM. ‡Withdrawn from market. CLINICAL TRIALS: †Phase III. §Never to phase III

This bacteria-related article is a stub. You can help Wikipedia by expanding it. v • d • e

This pharmacology-related article is a stub. You can help Wikipedia by expanding it. v • d • e

This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)