Tropomyosin beta chain is a protein that in humans is encoded by the TPM2 gene.[1][2]
Interactions
TPM2 has been shown to interact with RRAD,[3] PDLIM7[4] and TPM1.[5]
References
- ^ Hunt CC, Eyre HJ, Akkari PA, Meredith C, Dorosz SM, Wilton SD, Callen DF, Laing NG, Baker E (Aug 1995). "Assignment of the human beta tropomyosin gene (TPM2) to band 9p13 by fluorescence in situ hybridisation". Cytogenet Cell Genet 71 (1): 94–5. PMID 7606936.
- ^ "Entrez Gene: TPM2 tropomyosin 2 (beta)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7169.
- ^ Zhu, J; Bilan P J, Moyers J S, Antonetti D A, Kahn C R (Jan. 1996). "Rad, a novel Ras-related GTPase, interacts with skeletal muscle beta-tropomyosin". J. Biol. Chem. (UNITED STATES) 271 (2): 768–73. ISSN 0021-9258. PMID 8557685.
- ^ Guy, P M; Kenny D A, Gill G N (Jun. 1999). "The PDZ domain of the LIM protein enigma binds to beta-tropomyosin". Mol. Biol. Cell (UNITED STATES) 10 (6): 1973–84. ISSN 1059-1524. PMID 10359609.
- ^ Brown, H R; Schachat F H (Apr. 1985). "Renaturation of skeletal muscle tropomyosin: implications for in vivo assembly". Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 82 (8): 2359–63. ISSN 0027-8424. PMID 3857586.
Further reading
- Gunning P, Weinberger R, Jeffrey P (1997). "Actin and tropomyosin isoforms in morphogenesis.". Anat. Embryol. 195 (4): 311–5. PMID 9108196.
- Holtzer ME, Kidd SG, Crimmins DL, Holtzer A (1993). "Beta beta homodimers exist in native rabbit skeletal muscle tropomyosin and increase after denaturation-renaturation.". Protein Sci. 1 (3): 335–41. PMID 1304342.
- Höner B, Shoeman RL, Traub P (1992). "Degradation of cytoskeletal proteins by the human immunodeficiency virus type 1 protease.". Cell Biol. Int. Rep. 16 (7): 603–12. PMID 1516138.
- Chevray PM, Nathans D (1992). "Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun.". Proc. Natl. Acad. Sci. U.S.A. 89 (13): 5789–93. PMID 1631061.
- Prasad GL, Meissner S, Sheer DG, Cooper HL (1991). "A cDNA encoding a muscle-type tropomyosin cloned from a human epithelial cell line: identity with human fibroblast tropomyosin TM1.". Biochem. Biophys. Res. Commun. 177 (3): 1068–75. PMID 2059197.
- Libri D, Mouly V, Lemonnier M, Fiszman MY (1990). "A nonmuscle tropomyosin is encoded by the smooth/skeletal beta-tropomyosin gene and its RNA is transcribed from an internal promoter.". J. Biol. Chem. 265 (6): 3471–3. PMID 2303454.
- Widada JS, Ferraz C, Capony JP, Liautard JP (1988). "Complete nucleotide sequence of the adult skeletal isoform of human skeletal muscle beta-tropomyosin.". Nucleic Acids Res. 16 (7): 3109. PMID 3368322.
- Brown HR, Schachat FH (1985). "Renaturation of skeletal muscle tropomyosin: implications for in vivo assembly.". Proc. Natl. Acad. Sci. U.S.A. 82 (8): 2359–63. PMID 3857586.
- MacLeod AR, Houlker C, Reinach FC, et al. (1986). "A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism.". Proc. Natl. Acad. Sci. U.S.A. 82 (23): 7835–9. PMID 3865200.
- Gimona M, Watakabe A, Helfman DM (1995). "Specificity of dimer formation in tropomyosins: influence of alternatively spliced exons on homodimer and heterodimer assembly.". Proc. Natl. Acad. Sci. U.S.A. 92 (21): 9776–80. PMID 7568216.
- Bamshad M, Watkins WS, Zenger RK, et al. (1994). "A gene for distal arthrogryposis type I maps to the pericentromeric region of chromosome 9.". Am. J. Hum. Genet. 55 (6): 1153–8. PMID 7977374.
- Takenaga K, Nakamura Y, Sakiyama S, et al. (1994). "Binding of pEL98 protein, an S100-related calcium-binding protein, to nonmuscle tropomyosin.". J. Cell Biol. 124 (5): 757–68. PMID 8120097.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
- Shoeman RL, Sachse C, Höner B, et al. (1993). "Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.". Am. J. Pathol. 142 (1): 221–30. PMID 8424456.
- Zhu J, Bilan PJ, Moyers JS, et al. (1996). "Rad, a novel Ras-related GTPase, interacts with skeletal muscle beta-tropomyosin.". J. Biol. Chem. 271 (2): 768–73. PMID 8557685.
- Tiso N, Rampoldi L, Pallavicini A, et al. (1997). "Fine mapping of five human skeletal muscle genes: alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast.". Biochem. Biophys. Res. Commun. 230 (2): 347–50. doi:10.1006/bbrc.1996.5958. PMID 9016781.
- Gimona M, Lando Z, Dolginov Y, et al. (1997). "Ca2+-dependent interaction of S100A2 with muscle and nonmuscle tropomyosins.". J. Cell. Sci. 110 ( Pt 5): 611–21. PMID 9092943.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
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Proteins of the cytoskeleton |
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Actins (A1, A2, B, G1, G2)
Myosins (1A, 1B, 1C, MYH1, MYH2, MYH3, MYH4, MYH6, MYH7, MYH7B, MYH8, MYH9, MYH10, MYH11, MYH13, MYH14, MYH15, MYH16)
Tropomodulin (1, 2, 3, 4) · Troponin (T 1 2 3, C 1 2, I 1 2 3) · Tropomyosin (1, 2, 3, 4)
other related: Actinin ( 1, 2, 3, 4) · Arp2/3 complex · actin depolymerizing factors ( Cofilin ( 1, 2) · Destrin) · Gelsolin · Profilin ( 1, 2)
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Other
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type 1 and 2 ( Cytokeratin, type I, type II) · type 3 ( Desmin, GFAP, Peripherin, Vimentin) · type 4 ( Internexin, Nestin, Neurofilament, Synemin, Syncoilin) · type 5 ( Lamin A, B)
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Other
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