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Travoprost

 
Drug Info: Travoprost

Brand names: Travatan™Travatan® Z

Chemical formula:



Travoprost eye solution

What is travoprost eye solution?

TRAVOPROST (Travatan®) helps to reduce pressure in the eye for patients with increased pressure or open-angle glaucoma. Generic travoprost eye solution is not yet available.

What should I tell my health care provider before I take this medicine?

They need to know if you have, or have had, any of these conditions:
eye abrasion, infection, or inflammation
• wear contact lenses
• closed-angle glaucoma
• kidney disease
• liver disease
• an unusual or allergic reaction to travoprost or other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Contact lenses should be removed prior to using travoprost eye solution. Contact lenses may be reinserted 15 minutes following application of travoprost to the eye.

Travoprost eye solution is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Tilt the head back slightly and pull down the lower lid with the index finger to form a pouch. Try not to touch the tip of the dropper to your eye or into the pouch. Squeeze the prescribed number of drops into the pouch and gently close the eyes for 1—2 minutes. Do not blink. Use your doses at regular intervals. Do not use you medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What drug(s) may interact with travoprost eye solution?

No interactions with other medicines have been reported.

Do not use any other eye products without telling your prescriber or health care professional. Check before stopping or starting any of your medicines or non-prescription products.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking travoprost?

Report any serious side effects promptly. Stop using travoprost if your eyes get inflamed, painful or have a discharge and see your prescriber or health care professional as soon as you can.

This medicine may cause your eye, eyelashes, and eyelids to change color. Tell your prescriber or health care professional if this occurs. If only one eye is being treated with travoprost, a difference may develop between the treated and untreated eye in eyelash length, darkness or thickness, and/or color changes of the eyelid skin or iris. These changes may be permanent.

If you wear contact lenses, be sure to remove them before placing drops in the eye. Certain chemicals in the solution can be absorbed by contact lenses. Contact lenses may be reinserted 15 minutes following application of travoprost to the eye.

Visit your prescriber or health care professional for regular checks on your progress. Report any serious side effects promptly. Stop using travoprost if your eyes get inflamed, painful, or have a discharge, and see your prescriber or health care professional immediately.

Be careful not to touch the tip of the dispensing container onto the eye, or any other surface. Serious eye infections can result from contamination of eye solutions.

If you are using another eye preparation, there should be an interval of at least 5 minutes between use of travoprost and the other eye preparations.

Wear dark glasses if travoprost makes your eyes more sensitive to light.

What side effects may I notice from using travoprost eye solution?

Side effects that you should report to your prescriber or health care professional as soon as possible:
• any change in your vision
• inflamed or infected eyes or eyelids

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• burning, stinging, or discomfort immediately after using the solution
• changes in eye, eyelash, or eyelid color
• dry eyes
• increased flow of tears
• sensitivity of the eyes to light

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store the bottle at room temperature at 2—25 degrees C (36—77 degrees F). Throw away any unused medicine after the expiration date.

Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

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Wikipedia: Travoprost
Top
Travoprost
Systematic (IUPAC) name
propan-2-yl 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)
phenoxy]-but-1-enyl]-cyclopentyl]hept-5-enoate
Identifiers
CAS number 157283-68-6
ATC code S01EE04
PubChem 656627
DrugBank APRD01271
Chemical data
Formula C26H35F3O6 
Mol. mass 500.548 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C US

Legal status

Rx only (US)

Routes Topical (eye drops)
 Yes check.svgY(what is this?)  (verify)

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.[1] It is also known by the brand name of Travatan and Travatan Z, manufactured by Alcon Inc. Travoprost is a synthetic prostaglandin F 2α analogue. Its chemical name is isopropyl (Z)-7- [(1 R ,2 R ,3 R ,5 S )-3,5-dihydroxy-2-[(1 E ,3 R )-3-hydroxy-4-[(α,α,α-trifluoro- m -tolyl)oxy]-1- butenyl]cyclopentyl]-5-heptenoate.[2]

Side effects

Possible side effects of this medication are:

  • May cause blurred vision;
  • May cause eyelid redness;
  • May permanently darken eyelashes;
  • May cause eye discomfort;
  • May eventually cause permanent darkening of the iris to brown (heterochromia);
  • May cause a temporary burning sensation during use.
  • May cause thickening of the eyelashes.
  • May Cause inflamation of the Prostate gland, restricting urine flow (BPH).

References


Notes


 
 
Learn More
Travoprost eye solution
Solución ocular de travoprost
Travoprost Ophthalmic drops, solution

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Drug Info. Gold Standard. Copyright © 2008 by Gold Standard. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Travoprost" Read more