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TrEMBL, Translated EMBL is a very large protein database in Swiss-Prot format generated by computer translation of the genetic information from the EMBL Nucleotide Sequence Database database.
Computer translation is not entirely perfect, so proteins predicted by the TrEMBL database can be hypothetical, and many TrEMBL entries are poorly annotated. In contrast to Swiss-Prot which contains only proteins actually found in the wild, and PIR which is entirely unchecked.
TrEMBL is currently being combined with the above two databases in the UniProt Consortium.
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