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Triamcinolone

 
Sci-Tech Dictionary: triamcinolone
 
(′trī·am′sin·əl′än)

(organic chemistry) C21H27FO6 White, toxic crystals; insoluble in water, soluble in dimethylformamide; melts at 266°C; used as an intermediate for ion-exchange resin, wetting and frothing agent, and photographic developer.


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Drug Info: Nystatin; Triamcinolone
 

Brand names: Tri-Statin® II, Mycolog® II, Mytrex®, Myco-Triacet® II



Nystatin; Triamcinolone cream or ointment

What is nystatin; triamcinolone skin cream or ointment?

NYSTATIN; TRIAMCINOLONE (Mycolog® II, Mytrex®, Myco-Triacet® II, Tri-Statin® II) is a antifungal and corticosteroid cream or ointment. The combination treats Candida (yeast) infections of the skin and helps to reduce the swelling, redness, and itching that may occur with these infections. Generic nystatin; triamcinolone skin cream and ointment are available.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• large areas of burned or damaged skin
• skin wasting or thinning
• peripheral vascular disease or poor circulation
• an unusual or allergic reaction to nystatin, triamcinolone, other corticosteroids, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Nystatin; triamcinolone skin cream or ointment is for external use only; do not take by mouth. Follow the directions on the prescription label exactly. Wash your hands before and after use. If treating hand or nail infections, wash hands before use only. Apply a thin layer of cream or ointment to the affected area and rub in gently. When applying to the groin area, apply a limited amount and do not use for longer than 2 weeks unless directed to by your prescriber. Do not cover or wrap the treated area with an airtight bandage (such as a plastic bandage). Apply the cream or ointment for the full course of treatment prescribed, even if you think the infection is getting better. Use at regular intervals. Do not use your medicine more often than directed. Do not use this medicine for any condition other than the one for which it was prescribed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

Elderly patients are more likely to have damaged skin through aging, and this may increase side effects. Corticosteroid skin preparations should usually only be used for brief periods in older patients unless used under the supervision of a prescriber.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or take extra doses without advice.

What drug(s) may interact with nystatin; triamcinolone skin cream or ointment?

Tell your prescriber or health care professional about other skin products you are using. Do not apply nystatin; triamcinolone at the same site as other skin preparations without the advice of your prescriber.

What should I watch for while taking nystatin; triamcinolone skin cream or ointment?

Tell your prescriber or health care professional if your symptoms do not improve within 1 week when treating the groin area or within 2 weeks when treating the feet. It is important not to use more nystatin; triamcinolone cream or ointment than prescribed. When applying this product to the groin area, do not use for more than 2 weeks. Do not use on healthy skin or over large areas of skin.

Tell your prescriber or health care professional if you develop sores or blisters that do not heal properly. If your skin infection returns after stopping this cream or ointment, contact your prescriber.

Do not use an airtight bandage to cover the affected area unless your prescriber or health care professional tells you to.

If you are using this cream or ointment to treat an infection in the groin area, do not wear underwear that is tight-fitting or made from synthetic fibers such as rayon or nylon. Instead, wear loose-fitting, cotton underwear. Children being treated in the diaper area should not wear tight-fitting diapers or plastic pants. Also dry the area completely after bathing.

Do not get this cream or ointment in your eyes. If you do, rinse out with plenty of cool tap water.

What side effects may I notice from using nystatin; triamcinolone skin cream or ointment?

Side effects that you should report to your prescriber or health care professional as soon as possible:
• burning or itching of the skin
• dark red spots on the skin
• loss of feeling on skin
• painful, red, pus-filled blisters in hair follicles
• skin infection
• thinning of the skin or sunburn: more likely if cream or ointment applied to the face

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• dry or peeling skin
• skin irritation, burning or itching

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 2 and 30 degrees C (36 and 86 degrees F); do not freeze. Throw away any unused medicine after the expiration date.


Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

 
Wikipedia: Triamcinolone
Top
Triamcinolone
Systematic (IUPAC) name
(11β,16α)-9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
Identifiers
CAS number 124-94-7
ATC code A01AC01 D07AB09, D07XB02, H02AB08, R01AD11, R03BA06, S01BA05
PubChem 31307
DrugBank APRD00422
ChemSpider 29046
Chemical data
Formula C21H27FO6 
Mol. mass 394.434 g/mol
SMILES eMolecules & PubChem
Synonyms (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one; (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
Pharmacokinetic data
Bioavailability  ?
Protein binding 68%
Metabolism Hepatic
Half life 88 minutes
Excretion Fecal and renal
Therapeutic considerations
Pregnancy cat.

A (Au), C (US)

Legal status

POM(UK) -only(US)

Routes Oral, topical, IM, intra-articular, intrasynovial

Triamcinolone (trade names Kenalog, Aristocort, Nasacort, Tri-Nasal, Triderm, Azmacort, Trilone, Volon A, Tristoject, Fougera, Tricortone,Triesence;) is a synthetic corticosteroid given orally, by injection, inhalation, or as a topical ointment or cream.

Contents

Uses

Triamcinolone is used in the post-operative period of certain cosmetic surgery procedures, notably rhinoplasty. Injected into the subcutaneous area, it may help to alleviate stubborn swelling, inflamed sebaceous cysts, and scar tissue.

Triamcinolone is occasionally used to treat severe cases of hayfever.[1] Cream forms are used to treat keratosis pilaris, psoriasis, oral irritation after dental procedures. It is highly effective in the most severe cases of eczema, but may require a waiting period before subsequent treatments.Triamcinolone also used in case of severe arthritis, Lumbago sciatica. Injection is given to intra articular space of knee joing and also at the tip of the coccyx etc.[citation needed] The drug may also be used to treat diabetic retinopathy.[2]

Forms

Different triamcinolone salts are available, including acetonide, benetonide, furetonide, hexacetonide and diacetate.

Triamcinolone acetonide is a more potent type of triamcinolone, being about 8 times as effective as prednisone.

Side effects

Side effects of Triamcinolone include a sore throat, nosebleeds, increased coughing, headache, and runny nose. White patches in the throat or nose indicates a serious side effect. Symptoms of an allergic reaction include rash, itch, swelling, severe dizziness, trouble breathing.[3]

An additional side effect for women is a prolonged menstrual cycle.

References

Box and vial of Kenalog intra-articular/intramuscular
  1. ^ Hayfever (allergic rhinitis) - BUPA
  2. ^ Gómez-Ulla F, Marticorena J, Alfaro DV 3rd, Fernández M, Méndez ER, Rothen M. (2006). "Intravitreal triamcinolone for the treatment of diabetic macular edema.". Curr Diabetes Rev. 2 (1): 99-112. PMID 18220620. 
  3. ^ "Drugs and Treatments - Nasacort AQ Nasl - Patient Handout". WebMD. http://www.webmd.com/drugs/drug-16244-Nasacort+AQ.aspx?drugid=16244&drugname=Nasacort%20AQ. Retrieved on 2008-03-24. 

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Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Triamcinolone" Read more