Tropomodulin: Information from Answers.com

Tropomodulin is a protein which binds and caps the pointed end of actin, regulating the length of actin filaments in muscle and non-muscle cells. It functions in the presence of tropomyosin and nebulin to inhibit microfilament elongation. Inhibition of tropomodulin capping activity leads to dramatic increase in thin filament length from its pointed end.^[1]

Genes

References

^ Requirement of pointed-end capping by tropomodulin to maintain actin filament length in embryonic, http://www.nature.com/nature/journal/v377/n6544/abs/377083a0.html, retrieved 2009-04-10

External links

MeSH Tropomodulin

Proteins of the cytoskeleton

Human

Microfilaments
(ABPs)

Myofilament	Actins (A1, A2, B, G1, G2) Myosins (1A, 1B, 1C, MYH1, MYH2, MYH3, MYH4, MYH6, MYH7, MYH7B, MYH8, MYH9, MYH10, MYH11, MYH13, MYH14, MYH15, MYH16) Tropomodulin (1, 2, 3, 4) · Troponin (T 1 2 3, C 1 2, I 1 2 3) · Tropomyosin (1, 2, 3, 4) other related: Actinin (1, 2, 3, 4) · Arp2/3 complex · actin depolymerizing factors (Cofilin (1, 2) · Destrin) · Gelsolin · Profilin (1, 2)

Other	Wiskott-Aldrich syndrome protein

IFs

type 1 and 2 (Cytokeratin, type I, type II) · type 3 (Desmin, GFAP, Peripherin, Vimentin) · type 4 (Internexin, Nestin, Neurofilament, Synemin, Syncoilin) · type 5 (Lamin A, B)

Microtubules

Dyneins · Kinesins · MAPs (Tau protein, Dynamin) · Tubulins · Stathmin · Tektin

Catenins

Alpha catenin · Beta catenin · Plakoglobin (gamma catenin) · Delta catenin

Other

APC · Dystrophin (Dystroglycan) · plakin (Desmoplakin, Plectin) · Spectrin (SPTA1, SPTAN1, SPTB, SPTBN1, SPTBN2, SPTBN4, SPTBN5) · Talin (TLN1) · Utrophin · Vinculin

Nonhuman

Major sperm proteins · Prokaryotic cytoskeleton (Crescentin, FtsZ, MreB)

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