Helicases and gyrases both function to uncoil the supercoiling
of the two DNA strands. Moreover, gyrase is responsible for
adjusting the tension in the two strands so that they don't snap
while unraveling.
Helicases and gyrases both function to uncoil the supercoiling
of the two DNA strands. Moreover, gyrase is responsible for
adjusting the tension in the two strands so that they don't snap
while unraveling.
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The topoisomerase enzyme uncoils the double helical structure of DNA during its replication to form the replication fork. In eukaryotes both posive and negative supercoils get unbind by topoisomerase I & II respectively.
Topoisomerase isomerase unwinds DNA to form replication fork
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Helicase unwind the two DNA strands while topoisomerase unwind
and also rejoin the the two strands of DNA.