| U6atac minor spliceosomal RNA | ||||||||||
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U6atac minor spliceosomal RNA is a non-coding RNA which is an essential component of the minor U12-type spliceosome complex. The U12-type spliceosome is required for removal of the rarer class of eukaryotic introns (AT-AC, U12-type) [1].
U6atac snRNA is proposed to form a base-paired complex with another spliceosomal RNA U4atac via two stem loop regions. These interacting stem loops have been shown to be required for in vivo splicing [2]. U6atac is the functional analog of U6 spliceosomal RNA in the major U2-type spliceosomal complex[2].
References
- ^ Lorkovic ZJ, Lehner R, Forstner C, Barta A; (2005). "Evolutionary conservation of minor U12-type spliceosome betweenplants and humans.". RNA 11: 1095–1107. doi:. PMID 15987817.
- ^ a b Padgett RA, Shukla GC; (2002). "A revised model for U4atac/U6atac snRNA base pairing.". RNA 8: 125–128. doi:. PMID 11911359.
- Shukla GC, Padgett RA; (1999). "Conservation of functional features of U6atac and U12 snRNAs betweenvertebrates and higher plants.". RNA 5: 525–538. doi:. PMID 10199569.
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