| uroporphyrinogen III synthase | |
|---|---|
| Identifiers | |
| Symbol | UROS |
| Entrez | 7390 |
| HUGO | 12592 |
| OMIM | 606938 |
| RefSeq | NM_000375 |
| UniProt | P10746 |
| Other data | |
| EC number | 4.2.1.75 |
| Locus | Chr. 10 q25.2-26.3 |
Uroporphyrinogen III synthase is an enzyme involved in the fourth step of porphyrin metabolism, involved in the conversion of hydroxymethyl bilane into uroporphyrinogen III.
Heme synthesis—note that some reactions occur in the cytoplasm and some in the mitochondrion (yellow)
Pathology
A deficiency is associated with Gunther's disease.
External links
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