VOC may refer to:
- Volatile organic compound, a vaporous chemical
- Vereenigde Oost-Indische Compagnie (in Dutch) or Dutch East India Company (1602–1800), an international Dutch trading organisation
- the filename extension for Creative Voice files, a proprietary audio file format developed by Creative Labs for use by their Soundblaster sound cards
- Open-circuit voltage (VOC), the voltage between two terminals when there is no external load connected
- Vannes Olympique Club, a French soccer club
- V. O. Chidambaram Pillai (1872–1936), Indian lawyer, trade union leader, shipping magnate and freedom fighter
- Vancouver Organizing Committee, organizer of the 2010 Vancouver Olympics
- Voice of the customer, a term to describe the process of capturing a customer's requirements
- Victory over communism.
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