William Stark may refer to:
- William Stark(1724-1776), the older brother of Gen. John Stark, the hero of the Battle of Bennington.
- William Ledyard Stark (1853-1922), a Nebraska Populist politician.
- William Henry Stark (1851-1936), an industrial leader whose contributions helped the city of Orange, Texas develop financially.
- William Stark (physician) (1741–1770), an English physician and medical pioneer who investigated scurvy by experimenting on himself with fatal consequences.
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