Proposed by Francis Crick to observations that the 5′-base of the anticodon was capable of ‘wobble’ in its position during translation, allowing it to make alternative hydrogen bonding arrangements with several different codon bases.

Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.