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Zoledronic Acid

 
Drug Info: Zoledronic Acid
 

Brand names: Reclast®Zometa®

Chemical formula:



Zoledronic Acid injection (Paget's disease, Osteoporosis, Reclast)

What is zoledronic acid injection?

ZOLEDRONIC ACID reduces the release and breakdown of calcium from bone. It is used to maintain healthy bone and reduce the risk of fracture in patients with Paget's disease. This medicine is also used in women who are post-menopausal that have osteoporosis.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• aspirin-sensitive asthma
• dental disease
• kidney disease
• an unusual or allergic reaction to zoledronic acid, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Zoledronic acid is for injection or infusion into a vein. It is given by a healthcare professional, usually in a hospital or clinic setting. For Paget's disease or for Osteoporosis, the injection is given once a year.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What drug(s) may interact with zoledronic acid?

• antiinflammatory drugs (NSAIDs, such as ibuprofen and naproxen)
• certain antibiotics given by injection
• certain water pills or diuretics (examples include Bumex®, Demadex®, Lasix®, or furosemide)
cyclosporine
• parathyroid hormone
tacrolimus
teriparatide
thalidomide

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking zoledronic acid?

Visit your doctor or health care professional for regular checks on your progress. They may schedule blood tests to make sure you do not have unwanted side effects.

It is important to maintain a specific intake of calcium and vitamin D in your diet while receiving this medicine. Do not exceed recommended amounts for your condition. Talk with your doctor, pharmacist, or other health care professional about your dietary or supplement needs.

What side effects may I notice from receiving zoledronic acid?

Side effects that you should report to your prescriber or health care professional as soon as possible:
• constant jaw pain, especially burning or cramping
• eye inflammation, pain, or vision change
• muscle cramps or weakness
• pain or difficulty passing urine
• very stiff muscles, unable to move easily

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• bone pain
• confusion
• constipation
• fever
• joint pain
• loss of appetite
• nausea, vomiting
• redness, pain, swelling, or irritation at the injection site
• tiredness

Where can I keep my medicine?

This medication is only given in a hospital or clinic. You will not keep this medicine at home.

Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

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