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Always check the labels, but most over the counter sleep aids are nothing more than what amounts to Benadryl. ibuprofen is an anti inflammatory. I have always had sleep issues and have had to rely on sleeping pills and have taken the two together and been fine. But as I said always check the labels, because with many OTC drugs you never know everything that is in them. Or you could ask your pharmacist. They have computer programs that will check drug interactions.

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15y ago
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11y ago

There are over the counter sleep aid combination pills called Aleve PM. If you are taking regular Aleve and adding a prescription sleeping pill, you shouldn't have negative effects, but it is not recommended to mix Aleve PM with your prescription sleeping medication.

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Wiki User

9y ago

It seems as though ibuprofen could be taken with sleeping pills in general. The particular type of sleeping pill wasn't named in the question. To be on the safe side, check with your doctor or pharmacist.

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Wiki User

14y ago

If you are pregnant, you should be getting medication information directly from medical professionals and not from a wiki service. The term "sleeping pill" covers too many possibilities to permit anyone to give a responsible answer to this question.

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Wiki User

12y ago

Ibuprofen and Zopiclone have no known drug interactions, therefore they can be taken together without any worries at all.

Dr. Jacob M. Deese, MD

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13y ago

No. This can be very dangerous. Only do it with a Doctor's supervision and advice.

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9y ago

You can take sleeping pills and ibuprofen but try to take them about an hour apart.

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Q: Can you mix painkillers and sleeping tablets?
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