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Yes, you can. The popular brand of OTC pain reliever, Excedrin, is actually just that - a combination of these two drugs, plus the amount of caffeine equal to one cup of coffee.

For adults, if the pain is severe, you can take two aspirin and two acetaminophen at the same time, then alternate the two drugs every two hours afterwards. For example, after taking two of the aspirin and two acetaminophen, wait two hours, then take two aspirin OR two acetaminophen, then in two more hours, take two of the other. Do NOT continue this for more than one day without your doctors approval.

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14y ago
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15y ago

Yes, there should not be any issues with taking the two medications together as they do not directly interact.

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15y ago

Antibiotics shouln't affect any internal medicine. So, yah, I guess it would be ok. Check webmd.com to make sure.

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15y ago

Yes, there is no problem in taking those 2 drugs at the same time or on the same day.

Do not exceed 4000 mg of acetaminophen (Tylenol) per day.

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10y ago

They work in different mechanisms and can safely be taken together. Limit the dose of acetaminophen to 4 grams/day.

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Wiki User

16y ago

Yes you can.

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Q: Can you take Tylenol and antibiotics together?
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