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MALT lymphoma is a form of lymphoma involving the lymphoid tissue, frequently of the stomach. MALT lymphoma is a cancer of the B-cell lymphocytes. It usually affects older people who are in their 60s.
It is unusual for masses recognizable as tumors to be seen upon examination. Definitive diagnosis of MALT lymphoma requires a biopsy, in which a bit of tissue is removed from the stomach or other involved site.
It is not known if infectious agents also cause MALT lymphomas outside of the stomach.
MALT lymphomas are solid tumors that originate from cancerous growth of immune cells that are recruited to secretory tissue such as the gastrointestinal tract, salivary glands, lungs, and the thyroid gland.
Zucca, E., et al. "The Gastric Marginal Zone Lymphoma of MALT Type." Blood 96 (July 2000): 410-19.
it is essential that the pathologist determine whether or not the lymphoma has grown beyond the borders of the mucosa, which lines the stomach or other gland.
It may be the case that in these patients, the MALT lymphoma may have already progressed to a point where high-grade lesions, not observed in the original biopsies, were resistant to the initial treatment.
This is a type of cancer that isn't produced in the nodes but through other organs. Most patients diagnosed with malt lymphoma find that this cancer is generally diagnosed before it spreads to a larger area of the body.
Individuals who develop MALT lymphomas are more likely to develop other forms of cancer.
MALT lymphomas are then recognized as areas of inflammation or ulceration within the stomach.
In general, the prognosis for patients with MALT lymphomas is good, with overall five-year survival rates that are greater than 80%.
In general, these patients are treated with chemotherapy in a similar manner to patients with other types of lymphoma.