Can you cross a Gypsy horse with a Clydesdale horse?

You can cross breed just about any breed of horses. I would always recommend checking with a vet just to make sure. It also depends on which breed is going to be the stallion. For instance, although Gypsy Vanners and Clydesdales are both considered draft horses, Clydesdales can be HUGE (17 hands and above) whereas most Gypsies are 14 and 15 hands. If the stallion is the Clydesdale, that could create a pretty big foal for a Gypsy mare to carry. Always double check with a vet first.