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Drinking should be discussed before hand with the prescribing doctor. Depakote does make some people drowsy, and can cause some liver problems relatively quickly. It's best to discuss this before with the doctor.

You should not drink alcohol while taking Depakote, whether you have bipolar or not is not an issue. It's a matter of the medication, not the illness.

Personal Experience:

I take the 500mg depakote twice a day for epilepsy and know my limits. Depakote can easily make you drowsy and tired so whenever I decide to have alcohol I only have 1 or 2 light beers such as Bud Light, Coors Light, or Miller Light. Plus, I only drink once or twice a month. When I went to a dinner years ago a buddy decided to treat me to a beer. I decided to have a bottle of Heineken but pretty soon I started getting dizzy and tired.

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9y ago
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15y ago

No. Your information from the pharmacy should have included a warning against drinking alcohol while taking Depakote.

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13y ago

depakote increases the chance of liver damage from alcohol.

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12y ago

You need to check with your Doctor or Pharmacist as it will depend on what medications you are taking

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Q: Can you drink alcohol with a 250mg to 500mg daily dosage of Depakote?
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