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Not a very good idea! They are both prescribed for pain, so take one or the other. Mixing those two will make you feel awful.

No. Mixing the two can cause you to stop breathing. If you pass out while taking these two medications together, you risk vomiting, and then breathing in your vomit, and thus drowning in it. This happened the other day in the Emergency Room where I work at. Don't ever mix opiate medications, such as morphine and Vicodin. It's a really great way to die.

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12y ago
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13y ago

Ask a doctor or pharmacist before using any cold, allergy, pain, or sleep medication while taking Vicodin.

Vicodin can impair your thinking and reaction times, adding an antihistamine will increase this.

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14y ago

Yes you can it won't do anything i tried it because i read the promethizine would intensive the Vicodin effect but i didn't feel any different it just made me drowzey hope that helps any....

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11y ago

Yes my DR. prescribed me hydrocodone and promethazine together because the hydrocodone causes me to feel sick to my stomach. IT works great!

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12y ago

Yeah but its dangerous. Only take small amounts of the oxy. Its great though!!!

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11y ago

Yes, you can take them both. But you should take the Promethazine first to give it time to work because Norco can and will cause pretty bad nausea even if you eat before taking it.

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