There has been some speculation that grapefruit can have an effect on methotrexate levels in your body, but there is not any real evidence that it is true. There is not enough of a concern to list it in the medication precautions.
is it safe to take topiramate with co codamol, diazepam ,naproxen and lanszoprazole together
Absolutely not - Topamax or topiramate are anti-convulsants. It is a medication used to treat epilepsy seizures and migrane. You cannot just take a dose of this it can have very serious side effects!
yes
yes
The amount you were prescribed by your physician.
Yes, you should continue to take methotrexate unless your doctor advises you to stop.
Yes, sometimes vets do give methotrexate, but it is in combination with other medications, and usually in extreme cases. If you have human methotrexate, do not attempt to dose it to your dog. This should only be done under vet care. Methotrexate is fatal if not given correctly.
Yes, you can. You will actually be more likely to get infections, and get them worse, when on methotrexate. At some point, you will likely need antibiotics.
Ask your doctor.
You can. There is no interaction between these drugs.
vitamin c
Topiramate may cause birth defects. Use effective birth control while taking topiramate. Patients who become pregnant while taking topiramate should contact their physician immediately.