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There are no known interactions between these two drugs. Loratadine treats Allergies. ibuprofen is an anti-inflammatory and a pain reliever. They work on separate nerve receptors and do not affect each other. See your doctor or pharmacist for more information about your personal situation and other drugs that may interact with these two. This response has been given by a medical professional, but not a physician. Although this response has been checked for accuracy and has been researched, any advice given here does not take the place of your primary care provider. In an emergency, please dial 911 or your local emergency number. This response is provided under the terms and disclaimers of WikiAnswers and the author of this answer cannot be held liable for any misguided attempts to follow this advice without the observation or guidance of a licensed physician.

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16y ago
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Q: Can you take nurofen with loratadine?
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