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Well I did for 3 years until I developed a reaction to Tramadol and had to come off it. But, as both can depress your breathing reflex, it is important to check out your condition with a doc first.

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โˆ™ 2012-09-16 10:34:19
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Q: Can you take tramadol with anti-depressants?
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Can you take antidepressants and tramadol together?

No, antidepressants can interact poorly with the pain reliever tramadol.

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These drugs are contraindicated. Taking tramadol with SSRI antidepressants significantly increases your risk of a potentially fatal condition known as Serotonin Syndrome. This includes symptom such as hallucinations, confusion, rapid heartbeat, rise in body temperature which can be fatal, sweating, tremor, and rigidity. You also have an increased risk of having a seizure.You should not take tramadol when taking these antidepressants.

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I went to see a new physician once, other than my pain doctor. He did a drug test. The only things I had taken were, hydrocodone, Xanax and Tramadol. When the test came back, he asked me if I take antidepressants. I don't. It had to be the tramadol that showed up as a tryciclic antidepressant. Couldn't have been the others. SO, my answer is absolutely Yes, tramadol will show up as a tricyclics AD. It is noted in the literature that it does have antidepressant properties. Whether that is related, I am unsure. NREMT-P

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