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Conditions and Diseases
Cystic Fibrosis

Causes of cystic fibrosis?


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2009-01-07 08:05:15
2009-01-07 08:05:15

It is caused by either both parents being CF carriers or one parent having CF and the other being a carrier and then the children getting it genetically. However the parents do not have to have CF to be a carrier as it is a recessive trait (if they have one CF gene and one non-CF gene, they will not have CF but there is a chance their children may if the other parent is also a CF carrier). Cystic fibrosis is a genetic disease. That means people inherit it from their parents through genes (or DNA), which also determine a lot of other characteristics including height, hair color and eye color. Genes, found in the nucleus of all the body's cells, control cell function by serving as the blueprint for the production of proteins. The defective gene that is responsible for causing cystic fibrosis is on chromosome 7. To have cystic fibrosis, a person must inherit two copies of the defective CF gene—one copy from each parent. If both parents are carriers of the CF gene (i.e., they each have one copy of the defective gene), their child will have a 25% chance of inheriting both defective copies and having cystic fibrosis, a 50% chance of inheriting one defective copy and being a carrier, and a 25% chance of not having CF or carrying the gene. Approximately 30,000 people in the United States have cystic fibrosis. An additional ten million more—or about one in every 31 Americans—are carriers of the defective CF gene, but do not have the disease. The disease is most common in Caucasians, but it can affect all races. The severity of cystic fibrosis symptoms is different from person to person. The most common symptoms are: Very salty-tasting skin

Persistent coughing, at times with phlegmFrequent lung infections, like pneumonia or bronchitisWheezing or shortness of breathPoor growth/weight gain in spite of a good appetiteFrequent greasy, bulky stools or difficulty in bowel movementsSmall, fleshy growths in the nose called nasal polypsSometimes people are told that they have asthma or chronic bronchitis when they really have cystic fibrosis. New research shows that the severity of CF symptoms is partly based on the types of CF gene mutations (defects). Scientists have found more than 1,500 different mutations of the CF gene.

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Cystic fibrosis is an autosomal recessive genetic disease that causes dysfunction in the CFTR protein.

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One gene: the CFTR gene, with hundreds mutations that causes cystic fibrosis.

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If by vector you mean the organism which causes it, there is none. Cystic fibrosis is a genetic condition.

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What is cystic fibrosis? Cystic fibrosis is a life threatening disease.

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cystic fibrosis (: cystic fibrosis :) cystic fibrosis ^-^


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