Uracil doesn't make RNA unstable. In fact, since it is one of the 4 Nitrogen bases that make up the nucleotides in RNA it is part of a building block of RNA. It helps keep RNA together. I hope that answers your question.
The 2' hydroxyl group makes RNA unstable. This hydroxyl group can cleave an RNA backbone by reacting with a neighboring phosphate group on the same RNA.
The 2' free hydroxyl group,which is highly reactive makes RNA unstable.
mRNA
Post-transcriptional modification is a process in cell biology by which, in eukararyotic cells, primary transcript RNA is converted into mature RNA. A notable example is the conversion of precursor messenger RNA into mature messenger RNA (mRNA), which includes splicing and occurs prior to protein synthesis. This process is vital for the correct translation of the genomes of eukaryotes as the human primary RNA transcript that is produced as a result of transcription contains both exons, which are coding sections of the primary RNA transcript.
Both DNA and RNA exist as single and double strands. yet the structure of a DNA is more stable then RNA. The main difference between the two nucliec acids is that DNA contains Deoxyribose and RNA contains ribose sugar which has a free hydroxyl group in its pentose ring which makes it prone for hydrolysis, thereby making it more unstable than the DNA.
There are three primary types of RNA involved in protein synthesis: messenger RNA, transfer RNA and ribosomal RNA. Whereas most types of RNA are the final products of their genes, messenger RNA (mRNA) is an intermediate in the information transfer process
The sequence of ribonucleotides determines the primary structure of an RNA molecule.
Intronsare intervening sequence of DNA; does NOT code for a protein.Exons are expressed squence of DNA; codes for a protein.
trizol helps in maintaining the integrity of the RNA and keeps it intact since RNA is very unstable due to the presence of hydroxyl groups which gives it a free radical.
Increasing the ratio neutrons/protons in the nucleus the atom become unstable.
Post-transcriptional modification is a process in cell biology by which, in eukararyotic cells, primary transcript RNA is converted into mature RNA. A notable example is the conversion of precursor messenger RNA into mature messenger RNA (mRNA), which includes splicing and occurs prior to protein synthesis. This process is vital for the correct translation of the genomes of eukaryotes as the human primary RNA transcript that is produced as a result of transcription contains both exons, which are coding sections of the primary RNA transcript.
Both DNA and RNA exist as single and double strands. yet the structure of a DNA is more stable then RNA. The main difference between the two nucliec acids is that DNA contains Deoxyribose and RNA contains ribose sugar which has a free hydroxyl group in its pentose ring which makes it prone for hydrolysis, thereby making it more unstable than the DNA.
RNA itself difficult to handle because of its unstable nature. Unlike DNA, RNA has free 2'-OH group in their ribose sugar that make them highly reactive. Other than this, RNAse contamination is everywhere (during isolation RNAase from our skin can kill RNA).
There are three primary types of RNA involved in protein synthesis: messenger RNA, transfer RNA and ribosomal RNA. Whereas most types of RNA are the final products of their genes, messenger RNA (mRNA) is an intermediate in the information transfer process
The sequence of ribonucleotides determines the primary structure of an RNA molecule.
Intronsare intervening sequence of DNA; does NOT code for a protein.Exons are expressed squence of DNA; codes for a protein.
A ribosomes primary function is to produce or synthesize proteins from RNA.
One of the primary functions is to aid in synthesis of proteins.
An unstable government.
mRNA