Medication and Drugs
Depression and Bipolar Disorder

Does hydromorphone cause greater respiratory depression then morphine?


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A milligram of hydromorphine (brand name dilaudid) is approximately 5-7 times stronger than a milligram of morphine. Thus 1 mg of hydromorphone is more effective at treating pain and more likely to have side effects, such as respiratory depression than the same dose of morphine. People should be started on lower doses of hydromophone than morphine for initial pain management. However, once the relative strengths are taken into account, hydromorphone is about as likely to cause respiratory depression as morphine.