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Prehistoric (before written history). No way to know.

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14y ago
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14y ago

Alcohol has been drunk...and doubtless drunk to excess on occasion...for at least 5000 years. There is no record of the first person to exhibit liver disease as a result of drinking alcohol.

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Q: When was the first case of alcoholic liver disease?
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What are some of the symptoms of alcoholic liver disease?

In the case of the symptoms of alcoholic fatty liver disease include: weakness, loss of appetite, nausea, stomach pain, general sense of feeling unwell.


Causes and Symptoms of Fatty Liver Disease?

Excess fat in the liver is known as fatty liver disease. There are two types of fatty liver disease: alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD). Both forms of the disease can lead to permanent liver damage.Alcoholic Liver Disease (ALD)A very high percentage of individuals who abuse alcohol will develop a fatty liver. The amount of alcohol consumed and how long it is consumed before leading to the disease will vary among different people.Other factors that may contribute to the likelihood of developing ALD are obesity, diet, a history of Hepatitis C, or high levels of iron in the system.Nonalcoholic Fatty Liver Disease (NAFLD)NAFLD is fatty liver disease that is not brought on by alcohol and it is the most common cause of chronic liver disease in the U.S. Although it is an abnormal condition, it does not always damage the liver.Symptoms of Fatty Liver DiseaseThere are usually no symptoms in the beginning stages of fatty liver disease. In advanced cases there may be nausea, weight loss, fatigue, and mental confusion. The liver may be enlarged, and there may be pain in the upper right section of the abdomen. If cirrhosis occurs, the liver will begin to fail, causing fluid retention, yellowing of the eyes and skin, muscle wasting, and internal bleeding.Diagnosis of Fatty Liver DiseaseAn enlarged liver noticed during a checkup or a blood test showing elevated liver enzymes may lead to a suspicion of fatty liver disease. It may also show up on an X-ray or ultrasound. A liver biopsy is the only way to confirm it, however.Treatment of Fatty Liver DiseaseAt this time, there is no treatment for fatty liver disease. In the case of alcoholic liver disease the most important thing to do is stop drinking. For those who are overweight, gradual weight loss may decrease the amount of fat in the liver.


What is the liver disease caused by drinking heavily over many years?

Alcoholic hepatitis is an inflammation of the liver. Up to 35 percent of heavy drinkers develop alcoholic hepatitis. Symptoms may include loss of appetite, nausea, vomiting, abdominal pain and tenderness, fever and jaundice. In its mild form, alcoholic hepatitis can last for years and will cause progressive liver damage. The damage may be reversible if you stop drinking. In its severe form, the disease may occur suddenly, after binge drinking, and it can quickly lead to life-threatening complications.Alcoholic cirrhosis is the most serious type of alcohol-induced liver disease.Cirrhosis refers to the replacement of normal liver tissue with scar tissue. Between 10 and 20 percent of heavy drinkers develop cirrhosis, usually after 10 or more years of drinking. Symptoms of cirrhosis are similar to those of alcoholic hepatitis. The damage from cirrhosis is not reversible, and it is a life-threatening disease. Your condition may stabilize if you stop drinking.Many heavy drinkers will progress from fatty liver to alcoholic hepatitis and finally to alcoholic cirrhosis, though the progression may vary from patient to patient. The risk of developing cirrhosis is particularly high for people who drink heavily and have another chronic liver disease such as viral hepatitis C.source:http://www.liverfoundation.org/education/info/alcohol/


When was the first case of autoimmune disease reported diagnosed or recorded in history?

Wikipedia- cushing's disease.


What is the prognosis of 75 year old man who's been drinking alcohol heavily for 20 years and now has symptoms of enlarged liver bruising loss of appetite and a lot of weight extreme lethargy?

Liver Swelling due to Alcohol TreatmentIn order to avoid further damage to the liver, treatment for alcoholic hepatitis requires complete abstinence from alcohol. Mild alcoholic hepatitis may not require additional treatment. A person with moderate to severe alcoholic hepatitis must avoid medications that place additional stress on the liver and follow a liver disease diet. Severe alcoholic hepatitis requires admission to a hospital for treatment. Unless complications develop, the symptoms of acute alcoholic hepatitis usually resolve within a week.Treatment for alcoholic hepatitis includes:Stop drinking alcohol.Avoid acetaminophenAvoid aspirinMedication to prevent complications:Pentoxifylline (Trental)Medications for nausea and vomiting:Metoclopramide (Reglan)Ondansetron (Zofran)Prochlorperazine (Compazine, Compro)Vitamin supplements:FolateThiamineVitamin KEat a liver disease diet:Low protein dietLow fat dietThe essentials of the liver disease diet:High carbohydrate diet:Carbohydrates, rather than protein, are the major source of calories in this diet.Moderate fat intake:The increased carbohydrate and fat intake help preserve protein in the body and prevent muscle breakdown.Low protein diet:Protein is restricted to 1 gram of protein per kilogram of body weight per day.Severe liver disease may require carefully measured amounts of protein supplements.Vitamin B supplementsLow salt dietLiver Swelling due to Alcohol DietA person with alcoholic hepatitis may benefit from the following diet.The liver is essential for the digestion of all foods. In the presence of liver disease, the ability to effectively metabolize proteins, carbohydrates, fats, and vitamins can be compromised. A liver disease diet is one in which foods are selected in quantities which provide adequate nutrition, but protect the liver from overworking.Carbohydrates should be the major source of energy (calories) for individuals with liver disease. Proteins assist in tissue repair and prevent fatty infiltration of liver cells. Those with severely compromised liver function must limit their intake of protein. In this case protein is not properly broken down and waste products can build up in the bloodstream.Those with liver disease will often suffer from sodium imbalances. Manifestations of sodium imbalance include ascites (abdominal fluid build-up) and edema (swelling) of the extremities. In this case dietary sodium restriction is essential.The essentials of the liver disease diet:High carbohydrate diet:This is the major source of calories in this diet.Moderate fat intake:The increased carbohydrate and fat help in preserving the protein in the body and prevent muscle wasting.Low protein diet:Restrict protein to 1 gram of protein per kilogram of body weight per day.Severe liver disease may require measured amounts of protein supplements.Vitamin B supplementsLow salt dietLiver Swelling due to Alcohol Questions For DoctorThe following are some important questions to ask before and after the treatment of alcoholic hepatitis.Questions to ask before treatment:What are my treatment options?What are the risks associated with treatment?Do I need to stay in the hospital?How long will I be in the hospital?What are the complications I should watch for?How long will I be on medication?What are the potential side effects of my medication?Does my medication interact with nonprescription medicines or supplements?Should I take my medication with food?Questions to ask after treatment:Do I need to change my diet?Are there any medications or supplements I should avoid?When can I resume my normal activities?When can I return to work?What else can I do to reduce my risk for liver disease?How often will I need to see my doctor for checkups?What local support and other resources are available? What is alcoholic hepatitis?A person with alcoholic hepatitis has inflammation of the liver caused by the direct toxic effects of alcohol on the liver. Over time, damage to the liver can scar the liver, a condition called cirrhosis.What are the symptoms of alcoholic hepatitis?Common symptoms of alcoholic hepatitis include abdominal pain, loss of appetite, fatigue, abdominal swelling, jaundice, and dark urine.What is cirrhosis?A person with cirrhosis has severe liver disease that causes permanent damage to the liver, which can result in liver failure. Cirrhosis causes an irreversible scarring within the liver that compromises its ability to function. The most common causes of cirrhosis are alcoholism and hepatitis C. Serious complications of cirrhosis include gastrointestinal bleeding and liver failure.What are the symptoms of cirrhosis?Symptoms of cirrhosis include weakness, fatigue, swelling, abdominal pain, jaundice and abdominal swelling.How does the doctor treat cirrhosis?Treatment for cirrhosis includes the strict avoidance of alcohol, liver disease diet, vitamin supplements, and caution when using medications that are metabolized by the liver. Other options include surgery to control severe bleeding in someone with cirrhosis.There are different ways that alcohol can affect thebody.If you understand that the liver takes toxins out of thebody and converts them to a non toxic form that the bodycan easily dispose of...then you will understand this:1) over consuming alcohol in a short time period doesn'tgive the liver enough time to convert it to acetaldehyde,then to acetate, then to carbon dioxide and water.It is a multi step process to do this. If the alcohol isnot completely converted it can become toxic to the livercells.2) consuming alcohol in a long time period lead to thebuild up of fat inside the liver. The liver is surroundedby a tight membrane capsule. This fat causes pressureinside the liver that can damage the liver cells.3) some people are more sensitive to alcohol than otherare. Just like any other drug, some have no problem andothers can react to it. Some are even allergic to it.4) mixing alcohol with medications can cause aninteraction between them that will instantly damage theliver cells.Now for alcoholic fatty liver disease.Fat starts to build up inside the liver, but doesn'tcause a problem...this is known as simple fatty liver.However, as the fat continues to develop in the liver,it will damage the liver cells. The immune system ofthe body will respond to this damage and causeinflammation to develop inside the liver. Thisinflammation will cause the liver to enlarge in size.This is no longer simple fatty liver...it isAlcoholic steatohepatitis. Steato means fat,hepat means liver and itis means inflammation.If a person stops the alcohol and the inflammationis treated, then the liver cells can heal and theproblem can be reversed...up to this point.However, if this isn't the case and the liver cellsstart to die off and form scar tissue inside the liver,then it becomes a progressive disease known asCirrhosis of the liver. It cannot be reversed andthere is no cure....except a liver transplant.It depends on how far advanced a person is in thisdisease. That can only be determined by the doctorthrough a liver biopsy and other testing.Can alcoholic fatty liver cause sudden death?Yes it can and I will explain why.When the liver has Cirrhosis...this means thatscar tissue has formed inside the liver. The livertries to generate new liver cells, but the new cellsbunch up against the scar tissue. This scar tissueblocks the flow of blood through the liver on itsway back to the heart and also blocks the flowof blood to the functioning liver cells, so they dieoff, also. The blood that once flowed through theliver can back up into the portal vein and causepressure there (portal hypertension), it also backsup into smaller vessels not used to handling thisblood and the pressure from it and they can haveweak spots and balloon outward and break open.This vessels are known as varies. It is anextreme emergency then. The patient can bleedinternally or bleed out completely. Keep in mindthat the liver can no longer make clotting factorsefficiently to help the blood to clot and theenlarged spleen will trap the platelets inside ofit. People with Cirrhosis bleed and bruise veryeasily. Anyone with Cirrhosis can die suddenly.Also, people with Cirrhosis can have a build up oftoxins reaching the brain...especially ammonia.Without medication to help remove this toxin fromthe body...they can go into a coma and die.(Any blood in the sputum, vomit, rectal area, orbelly button area...bleeding from the nose, etcshould be checked immediately)


How is the Wilson disease treated?

i have Wilson's disease. if caught early, it is usually treated with copper chelation therapy and zinc to counteract the copper absorption, and rarely is there an issue. BUT sometimes, it is not caught until there is a problem, especially when there is no knowledge of a family history. My sister was the first to be diagnosed. Because it is genetic, my brother and I were both screened. in my case, liver damage was already done. i have cirrhosis of the liver, and will need a liver transplant. my sister passed away. when i get the transplant, i can look forward to being one of the lucky people who can start over with an undamaged liver, who can control the disease with just zinc and syprine alone. hope this helped!


Who had the first case of celiac disease?

It was found in World War II. Soldiers were the first to be diagnosed.


What can cause high AST and LDH in liver function test?

In my case, I was told "non-alcoholic fatty liver." High blood cholesterol may cause high SGOT/AST and a specific LDH "type" (they can tell from whence the LDH originates) may be elevated. If they said liver, then fatty liver is usually the culprit. Habitual alcohol or certain medication use may cause fatty liver as well. Losing weight is said to help lower those two. Lowering blood cholesterol is important to help the "fatty liver" lessen it's load. In my case, years pass and more bloodwork reveals the same, plus leukemia and lymphoma. I am in poor general health, so I think the high AST & LDH are from the fatty liver and not the cancers. A CBC will inform your doctor if there are abnormalities that would point him/her away from fatty liver.


What is meant by the word alcoholic as in the person?

It refers in this case to a person who has an addiction to alcohol


What country has not had a case of foot and mouth disease?

There is no country that has not had at least 1 case of foot and mouth disease. This disease is a very common viral infection.


What has the author Kathryn Nash written?

Kathryn Nash has written: 'Hepatology' -- subject(s): Liver Diseases, Diseases, Case studies, Case Reports, Problems and Exercises, Liver


Why was there so many alcoholic drinks in the civil war?

So that the men can be brave enought to fight the battles, which, in that case helped them go back out to fight.