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The surface immunoglotulin that serves as the B-Cell antigen receptor (BCR) has two roles in B-cell activation. First, like the antigen receptor on T cells, it transmits signals directly to the cell's interior when it binds antigen. Second, the B-Cell antigen receptor delivers the antigen to intracellular sites where it is degraded and returned to the B-cell surface as peptides bound to MHC class II molecules.
Wiki User
∙ 12y ago
Wiki User
∙ 13y agoA naive B cell (has not encountered a pathogen that it can bind to) resides in your secondary lymph system. It expresses mainly IgM and IgD antibodies on its cell surface. A bacteria that enters your blood system will pass through your lymphatic system. When the naive B cell that recognizes a specific bacteria with it's antibody it will engulf it and present its peptides on MHC class II. However, this is generally insufficient to activate the B cell. It requires the help from a CD 4 T cell, more specifically Th2. Th2 cell that was activated from a dendritic cell will activate the B cell mainly with cytokines IL-4, IL-5, IL-10. This will fully activate the B cell into proliferation into plasma B cells and memory B cells. The plasma cell will undergo somatic hypermutation to increase specificity and isotype switching (IgA, IgE or IgG).
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Antigens cause immature B cells to?
When a B cell detects an antigen, it will engulf it and then display it on its cell surface with an MHC molcule. This antigen/MHC combination is then detected by a T cell - which will send signalling molcules to B cells to multiply and mature into plasma cells (which create antibodies against the antigen) and memory B cells (which 'remember' the antigen for next time).They become plasma cells
Which two mature blood cell types descend from myeloblasts?
B lymphocyte (B Cell)
The cytoplasmic structure in a bacterial cell is the a. cell wall b. nucleoid c. plasma membrane d. ribosomes?
b-nucleoid
What is the difference between a B cell and a memory B cell?
A plasma B cell is a B cell that has been activated to proliferate and produce antibodies against a specific antigen. A memory B cell is a B cell that lives a long time after an infection to provide long lasting immunity against that specific antigen. They both originate from the same B cell in your secondary lymph system. Once activated the specific B cell will proliferate into plasma B cells and memory B cells.
Another name for plasma membrane?
A cell membrane is also known as a plasma membrane or cytoplasmic membrane. The cell membrane separates the interior of a cell from its outside environment. The main function of a cell membrane is to protect the cell from its surroundings.
A mature B cell that mass produces antibodies is called a?
B effector cell. plasma cell
How is immunoglobulin made?
Immunoglobulins, more commonly referred to as antibodies.- Immunoglobulins/antibodies are synthesized by plasma cells which is a specialized type of B-cell. Immature B-cells are produced in red bone marrow and then migrating to the spleen where some of them mature to a mature B-cell. A mature B-cell can differentiate into either a memory B-cell or a plasma cell."- In human adults, Immunoglobulins are synthesized by plasma cells (specialized type of B-cell) which in turn originates from red bone marrow in large bones (eg. femur).
Are plasma cells specialized B cells?
yes . the memory b cell divide rapidly forming new plasma cell
Antigens cause immature B cells to?
When a B cell detects an antigen, it will engulf it and then display it on its cell surface with an MHC molcule. This antigen/MHC combination is then detected by a T cell - which will send signalling molcules to B cells to multiply and mature into plasma cells (which create antibodies against the antigen) and memory B cells (which 'remember' the antigen for next time).They become plasma cells
Where do lymphocytes mature so they can attack?
T-Cell mature in Thymus B-Cell mature in Bone Marrow
Which two mature blood cell types descend from myeloblasts?
B lymphocyte (B Cell)
What blood cell can become an antibody-secreting cell is?
The cell which can secret antibody are called B-Lymphocytes. Those cells are generally called as B-Cells.
Which cell develops into a plasma cell?
Stem cells develop into plasma cells and B cells also turn into plasma cells. Plasma cells have been exposed to an antigen and then produces and secretes antibodies.
What the difference between a b cell and a b memory cell?
A plasma B cell is a B cell that has been activated to proliferate and produce antibodies against a specific antigen. A memory B cell is a B cell that lives a long time after an infection to provide long lasting immunity against that specific antigen. They both originate from the same B cell in your secondary lymph system. Once activated the specific B cell will proliferate into plasma B cells and memory B cells.
Who is responsible for antibody production?
Naiive B cells are lymphocytes that have not yet been exposed to antigen. Once it can identify a particular antigen, it will undergo production of antibodies and become a mature B cell. Mature B cells are split into two categories: plasma B cells and memory B cells. Plasma B cells will continue to produce large amounts of antibodies. Memory B cells are stored so that the next time you encounter the same antigen, it can start producing antibodies much quicker because it remembered from the previous encounter.
What is the site of b lymphocyte and plasma cell formation?
Bone Marrow
What subgroup of the b cell clone that secretes antibodies?
plasma cells
