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The hydrolysis rate of prodrugs can be slowed down with the usage of sterically hindered esters and the use of long-chain fatty acid esters.
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How can the hydrolysis rate of prodrugs be accelerated?
If the base hydrolysis mechanism is important, an electron withdrawing group can be attached to the prodrug. If the acid hydrolysis mechanism is important, an electron donating group can be attacked to the prodrug.
Will introducing a competitive inhibitor change the rate of reaction?
It slowed the reaction rate down
What would happen if the rate of mutation slowed down?
Fewer new variations would arise.
What is the theoretical rate constant value for hydrolysis of ethyl acetate?
The rate constant value for the acidic hydrolysis of ethyl acetate is in 10-3 and for alkaline hydrolysis is in 10-5.
What does atropine do the heart?
It blocks the vegus nerve/ parasympathetic heart. This means that the heart rate can not be slowed down.
Why is the pulse rate the lowest when you are at rest?
because you aren't moving your body therefore it's slowed down.
Rate of bone loss during aging can be slow by?
bone loss can be slowed down by exercise, calicum, and vitamin D
How might the rate of photosynthesis be affected by increasing its thickness?
The rate of photosynthesis would be slowed down by increasing the thickness of a leaf. Leaves that are broad and thin offer the best conditions for the process.
Does lignocaine affect heart rate?
Yes, it can cause a sinus bradycardia (slowed heart rate).
What effect do hydrolysis enzyme's have on the rate at which large organic molecules break down?
The Enzymes speed up the process in which orgaic molecules breakown. They help the molecules break down. Therefore speeding up the process. Thats the Low-down. Hope it helped :)
How do tides on the earth slow down the Moon's rate of revolution?
The tides don't. A large enough earthquake could; like the one that recently hit Japan earlier this year; it slowed down the earth's revolution by a couple of milliseconds.
How does atropine work?
Anticholinergic agent/ parasympatholytic that inhibits the action of acetylcholine at the postganglionic parasympathetic receptor sites. Increases the heart rate in life threatening bradyarrhythmias.
