How can you decrease the glomerular filtration rate?

Answer 1

gfr is the net results of the balance between hydrostatic pressures &colloid osmotic pressures of intra vascular compartment & within the Bowman's capsule,where the net pressure gradient is towards filtration.i.e. "Net filtration pressure".Any method which will reduce this net filtration pressure will reduce GFR.That can be achieved by increasing the plasma globulin ad albumin level(increase colloid osmotic pressure),hypotension and addition of vasocostrictor at afferent and vasodialtors at efferent tubule(reducing capilary hydrostatic pressure) or obstructing the free flow of urine(increasing Bowman's casular hydrostatic pressure)