It's impossible, my friend. In Pokemon Sapphire the Kanto, Johto, and Sinnoh regions are inaccessible. The above statement is correct. However, you could be talking about the two islands that can be visited. There are only two other 'regions' in Pokemon Sapphire and they consist of a few steps of land. These are accessed when you receive a Nintendo event for a certain Pokemon to be unlocked - either Deoxys or Latios. Those two Pokemon can be caught on their respective islands, which can almost be counted as other regions.
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