How does chemical stability of the drugs in the gastrointestinal tact affect the bio-availability of the drugs?
Bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, so we need chemically stable drug in order to increase the chance of drug absorbance and thus increased bioavailability.
The stability of a drug is the ability of the drug to maintain its chemical, physical, therapeutic and toxicological properties throughout its shelf life. Often times environmental and other unexplainable factors affect the stability of drugs by causing degradation of either the active ingredient of the drug product or the excipients, reducing the bioavailability of the drug or changing the physical appearance of the drug.
The factors that affect stability can vary depending on the object. One factor that affects stability is the center of gravity. Factors that affect chemical stability include environmental factors and decomposition.
Many factors can contribute to affect the bioavailability of the orally administered drugs. Briefly, these includes gastric emptying rate, intestinal transit time, hepatic first pass metabolism, and gastrointestinal and hepatic blood flow etc. apart from these factors, disease conditions, diet and dosage form also contribute in alteration of the bioavailability of the drugs.
Yes the government can affect the stability of a business
They can still have different bioavailability (the amount of drug that is delivered to the site of action and the rate at whcih it is available). Pharmacetical equivalents do not have to have the same release mechanisms, and can therefore affect their bioavailability.
Any part of the gastrointestinal system can be affected by vasculitis, including the liver
Gastrointestinal diseases (including gastric ulcers) affect an estimated 25-30% of the world's population.
produces chemical stability; therefore increases E- or activation energy. In this case, you have a noble gas and are trying to strip electrons from it.
weather, erosion, deposition, compaction, living beings activity, acid rains, cementation, water contact, etc.
I think that most business have problems when the stability of the governemnt changes because so I think it most of the stability government will affect the business
They affect the kidneys, liver and gastrointestinal tract. Eventually they affect the brain, but secondary to these systems.
The conditions that affect physical stability are heat, temperature, compression, pressure, and the molecular structure.
Somatization affects the gastrointestinal, nervous, cardiopulmonary, or reproductive systems.
they affect the stability of th rocket flight
because we are one!!
Ligaments are factors that affect the stability of the foot. The spring ligament, deltoid ligament, and talocalcaneal interosseous ligament are most important for arch stability.
loss of lives, resources, stability
The weathering will lower the stability of the landform.
If you are passionately in love with someone in your family, it will affect the appearance of your children and their mental stability
Change in government regulation affect on buniess performance and business stability.
This disease affect the gastrointestinal system mainly. Next is skin. Though the viral infections are usually generalised infections.
It doesnt fack you
Chemical affect animals in different ways. Some chemical pollutant can kill the animal or make it defective.
depends on the chemical
Salmonella is generally found in the gastrointestinal tract. It can move into the bloodstream and affect internal organs and other systems.
the lower the center of gravity , the more stable it is
i need to know!! plz tell me!
Microwaving the food conserves much of the thiamin.
Physical and chemical weathering affect the Earth because your face !!!!!!!!!!!!!!
You are a chemical! So actually you are the chemical!
Eucalyptus, both the plant and the essential oil, is toxic to dogs - it causes salivation, nausea and other gastrointestinal problems.
personality traits teachers support emotional stability
water, air, and climate.
Please rewrite. We don't know what you listed.
no idea for your assignment today
By adding poles and zeros to the transfer function of a system we can affect its root locus and also the stability. If we add a valid zero to the T.F. it will shift the root locus towards left side of the s-plane and thus the stability increases. And if we add a valid pole reverse process of that of adding zero occurs... Ashish Sharma Astt. Professor
the children may affect on chemical technology cause by addicted to a example laptop,computer
Imports and exports affect economic growth and currency stability by proving the country or city with their own form of income. If a country only imported things for their country all their currency would be going to the place that is exporting the goods to them therefore unbalancing their currency stability. Likewise, if a country only exports things they are promoting their economic growth and currency stability but they will still need some things to… Read More
yes it's true
We cannot answer you question if you do not tell us what the listed causes are.
Droughts, floods, and heat waves
If the centre of gravity falls outside of the base, it will topple over.
they do that buy helping the chemical reaction
Practically, there are some factors that affect the frequency stability of Variation in temperature Oscillator • Circuit Components - Values of R, L and C changes with temperature • Transistor Parameters - causes variation in transistor parameters • Supply Voltages - Variations in power supply • Stray Capacitances • Output Load - Variations of load causes a change in effective resistance • Inter‐element Capacitance
A catalyst affects the speed of a chemical reaction. If the chemical reaction gives off heat, the reaction may affect the temperature, but the catalyst by itself doesn't affect the temperature.
Wider gives the machine more stability and load carrying ability
light heat oxygen microorganisms water loss water gain
The neutrons do not affect how the atom interacts with other atoms, but they do have an effect on the mass and stability of the nucleus.
the monomer - the H2O = the polymer .... ect. = polymer chain - einstein24