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If the lethal gene is recessive, and the parent carrying it is heterozygous for that gene, it can be passed down to offspring in the recessive form. If the mate of the parent happens to be carrying the same gene heterozygously, 50% of offspring will be expected to inherit the recessive lethal gene heterozygously. 25% of the offspring will be expected to inherit the lethal gene homozygously, leading to death. The remaining 25% of offspring we will expect to homozygously inherit the non-lethal gene. 1:2:1 ratio

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14y ago
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13y ago

Mutations can be lethal due to the fact that different defects affect different functions of an organism. If this organism which the mutation affects is vital for survival, it is more than likely that this mutation will result as fatal. For example, a mutation that affects the production of enzymes. Without enzymes, your body would not have mechanisms of defence, or storage. Mutations are potentially dangerous, but some may end up being rather benefical!

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13y ago

A lethal allele results in actual fatality if it is the dominant or only allele in an organism's genotype.

Most lethal alleles are recessive, however, so they are rarely expressed in an organism and get masked by a dominant allele, resulting in the nonlethality of that gene. (i.e. something else covers them up, so the gene isn't lethal and the organism suvives). Hence, such an allele can be passed on for many generations before actually being expressed in offspring.

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10y ago

When it is recessive and masked by a dominant allele. At least until it become homozygous recessive.

Dominant = L

recessive = l

Ll = masked

ll = homozygous recessive

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Q: How can a lethal gene be passed from one generation to the other?
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