A complete medical history, physical, neurological exam, electrical tests, blood and urine tests, challenge tests and genetic tests.
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Hyperkalemic PP is also called potassium-sensitive PP.
The gene for hyperkalemic PP affects virtually all who inherit it, with no difference in male-vs.-female expression.
The normal gene is responsible for a muscle protein controlling the flow of sodium during muscle contraction.
A parent with the gene has a 50% chance of passing it along to each offspring, and the likelihood of passing it on is unaffected by the results of previous pregnancies.
A person with periodic paralysis experiences sudden onset of weakness, which gradually subsides, only to return again later.
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Periodic paralysis disorders are genetic disorders that affect muscle strength. There are two major forms, hypokalemic and hyperkalemic, each caused by defects in different genes.
Periodic paralysis (PP) is the name for several rare, inherited muscle disorders marked by temporary weakness, especially following rest, sleep, or exercise.
With hypokalemic periodic paralysis an attack of weakness can be induced by administering glucose and insulin with exercise. These tests are potentially hazardous and require careful monitoring.
Muscle weakness,paralysis,drooping eyelids or a weak voice.
Familiar (genetic) Periodic paralysis comprises a group of rare genetic diseases that cause symptoms such as muscle weakness, muscle stiffness, and complete paralysis. While there more than 30 different strains of periodic paralysis have been identified, the most common include: * Hypokalemic Periodic Paralysis- Caused by reductions in potassium levels, causing the patient to experience weakness and paralysis after eating certain foods or strenuous exercise. * Thyrotoxic Periodic Paralysis- Associated with an overactive thyroid gland. * Hyperkalemic Periodic Paralysis- Weakness, paralysis, and stiffness is experienced after fasting or exercise. * Paramyotonia Congenita- Causes muscle stiffness or weakness as a result of cold temperatures, activity, or low potassium. * Potassium Aggravated Myotonia- Causes muscle stiffness as a result of ingesting potassium. * Malignant Hyperthermia-Caused by a reaction to drugs used in general anaesthetics. While diagnosis of partial paralysis can be extremely difficult, research is offering some new developments. Incidents of partial paralysis can be avoided by staying away from certain hormones, foods, and medications.
The level of potassium in the blood rises slightly or is normal.
The level of potassium in the blood falls in the early stages of a paralytic attack.
Hyperkalemic PP is also called potassium-sensitive PP.
He developed what was diagnosed as infantile paralysis in 1921, before he was elected governor or President.
Electrical tests of muscle and a muscle biopsy show characteristic changes.