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It is recommended to cook a pork tenderloin for 1 to 1.5 hours per pound when using a low temperature such as 265 degrees. For a 2.5 lb. tenderloin this would be about 2.5 to almost 4 hours. The internal temperature of the tenderloin must reach at least 165 degrees to be considered safe to eat.

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10y ago
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14y ago

The typical bake time for a pork tenderloin is about 20 minutes per pound, so I would say about 50 minutes at 350 degrees. But times and temperatures vary depending on ovens and altitude.

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Q: How long do you cook a 2.5 lb pork tenderloin at 265 degrees?
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