How long does azithromycin work?
The standard answer is that azithromycin is actively fighting infection for 10 days during a course of normal therapy, which includes both the 3 and 5 day dosing of the medication. This answer is based on the drugs long half life, which results from its uptake by phagocytes. (Both 3 and 5 day dosing schedules result in a total of 1.5 grams of azithromycin being delivered to the patient.)
Apparently, Azithromycin accumulates in body tissues more so than other drugs. As a result, it hastens results. Treatment for a common infection that normally would take 7-10 days only takes 3-5 days with this drug. Reference: "Azithromycin: An antibiotic with unusual properties" in the European Journal of Clinical Microbiology & Infectious Diseases,