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This depends on many factors such as your size and tolerance. Also some Adderall are xr that are time release, these take effect for a lot longer. I can tell you that I am prescribed to adderall but only take 15mgs. About 5 times a month and am a 200 pound man and they usually do not start to wear off until 6 to 8 hours. As you can see there are many contributions to this but I think it would be safe to say that 6-8 hours is the typical affective time of these adderall. Hope this helps

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9y ago
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15y ago

I have noticed that I take my Adderall xr 20 mg at 7:30am and by Noon or so, it feels like it is gone....

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14y ago

in four days, when you haven't bathed or eaten and suddenly realize you're naked, halfway up a telephone pole.

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Q: How soon does a 20 mg XR Adderall wear off?
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